Tuesday, April 8, 2008

PRBB participates at the “Live Research” fair

What is the genome? How different is one person from another one and why? How can we generate more than 150,000 proteins from only 30,000 genes? These and other related questions will be answered by scientists from the PRBB centres next April 10 and 11 at the fair “Live Research”, organized by the Parc Científic de Barcelona (PCB). Around 1,600 visitors are expected in the sixth edition of this free science fair that aims to show the research taking place in the different centres and research institutions of Barcelona.

I will be there, so I hope to post some pictures and a summary next week. I will also tell you if I succeeded in extracting my own DNA...!

Friday, April 4, 2008

What's PET? Molecular Imaging service from the IAT




The Institute of Advanced Technology (IAT is one of the most technologically advanced centres in southern Europe in molecular imaging such as positron emission tomography (PET and magnetic resonance. It was the first entity to be based at the PRBB in 2004, and it offers its services to the scientific community and the pharmaceutical industry.

PET, which is commonly used in oncology and neurosciences, consists on visualising molecules within the organisms in vivo thanks to the fact that these molecules are labelled with a radioactive isotope which emits positrons. It is used for the detection of tumours and the analysis of their development in response to treatment. In neurosciences it is useful for measuring the activity of new psychoactive drugs.

The IAT has a cyclotron (of 23 tons of weight) inside a bunker in the basement. The cyclotron is a particle accelerator that converts stable elements into radioisotopes, which are then transferred to the radiochemical laboratory. Once in the laboratory, the radiotracers (the molecules of interest with a radioisotope incorporated) are synthesized. The radiotracers are then administered to the patient or the laboratory animal, who is subjected to the PET or micro-PET, where the radiation emission is converted into an image in a non-invasive manner.

The IAT, currently with a staff of 22 people, is a non-for-profit foundation fostered by the ‘CRC Corporació Sanitària’ group, the Municipal Institute for Health Assistance (IMAS), the CLINIC Corporation, and the Foundation ‘Institut de Recerca Hospital Universitari Vall d’Hebron’.